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KMID : 0903520070500010068
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2007 Volume.50 No. 1 p.68 ~ p.71
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Hypoglycemic Effect of Nutraceuticals Extract Supplementations on NIDDM Patients
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Kim Hyun-Sook
Kim Dae-Jung
Hwang Ha-Jin
Lee Hyun-Joo
Choe Myeon
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Abstract
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Cordyceps militaris, Artemisia capillaris, and Fagopyrum esculentum have been known to maintain normal blood sugar levels in folk medicine. We investigated the effects of these nutraceuticals extract supplementations on fasting and postprandial blood glucose in diabetes mellitus patients. The study population consisted of 50 diabetes subjects with a mean fasting blood glucose of 186.8 ± 6.2 mg/dl and postprandial blood glucose of 292.8 ± 10.3 mg/dl. They consumed 3 tea bags (3 g per meal) of the extract of selected plants for 17 weeks. Patients treated with nutraceuticals extract supplementation showed a significant decrease of fasting blood glucose (118.4 ± 3.9 mg/dl) and postprandial blood glucose (160.5 ± 4.0 mg/dl) in 7 weeks. Nutraceuticals extract supplementation caused a significant decrease of 36.5% and 45% in fasting and postprandial blood glucose levels, respectively, and also significantly decreased HbA1c levels. This study shows that extract of nutraceuticals supplementation significantly lowered the fasting and postprandial blood glucose levels in NIDDM patients. These effects presumably contribute to the hypoglycemic activity.
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KEYWORD
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diabetes mellitus, HbA1c, nutraceuticals, hypoglycemic effect
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